Ovarian mast cells migrate toward ovary-fimbria connection in neonatal MRL/MpJ mice
نویسندگان
چکیده
منابع مشابه
Mast cells migrate from blood to brain.
It is well established that mast cells (MCs) occur within the CNS of many species. Furthermore, their numbers can increase rapidly in adults in response to altered physiological conditions. In this study we found that early postpartum rats had significantly more mast cells in the thalamus than virgin controls. Evidence from semithin sections from these females suggested that mast cells were tra...
متن کاملGenomic Analysis of the Appearance of Ovarian Mast Cells in Neonatal MRL/MpJ Mice
In MRL/MpJ mice, ovarian mast cells (OMCs) are more abundant than in other mouse strains, and tend to distribute beneath the ovarian surface epithelium at birth. This study investigated the factors regulating the appearance of neonatal OMCs in progeny of the cross between MRL/MpJ and C57BL/6N strains. F1 neonates had less than half the number of OMCs than MRL/MpJ. Interestingly, MRLB6F1 had mor...
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Increased number of mast cells at the site of infection is widely regarded as important host defense against parasites. The kinetics of mucosal mast cells and connective tissue mast cells responses were studied in the intestines of 68 female CFLP mice infected with 100 Schistosoma mansoni cercariae. The number of mucosal mast cells and the connective tissue mast cells increased from week 3 and ...
متن کاملmast cells kinetics during experimental schistosomiasis mansoni in mice
increased number of mast cells at the site of infection is widely regarded as important host defense against parasites. the kinetics of mucosal mast cells and connective tissue mast cells responses were studied in the intestines of 68 female cflp mice infected with 100 schistosoma mansoni cercariae. the number of mucosal mast cells and the connective tissue mast cells increased from week 3 and ...
متن کاملDistinguishing Mast Cell Progenitors from Mature Mast Cells in Mice
Mast cells originate from the bone marrow and develop into c-kit(+) FcɛRI(+) cells. Both mast cell progenitors (MCp) and mature mast cells express these cell surface markers, and ways validated to distinguish between the two maturation forms with flow cytometry have been lacking. Here, we show that primary peritoneal MCp from naïve mice expressed high levels of integrin β7 and had a low side sc...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0196364